• 7 Posts
  • 1.58K Comments
Joined 2 years ago
cake
Cake day: June 1st, 2023

help-circle




  • GissaMittJobb@lemmy.mltoGreentext@sh.itjust.worksAnon goes on a diet
    link
    fedilink
    arrow-up
    99
    arrow-down
    2
    ·
    edit-2
    5 days ago

    Yep, that’s leptin resistance for you. Obesity is really a hormonal condition, and this is why GLP-1 inhibitors are so effective - they actually treat the hormonal condition and allow the recipient to manage their food intake without having their body hormonally work against them.

    A layman’s explanation (to be clear, I am the layman) of my best understanding of the subject:

    Hunger is controlled by 2 hormones:

    • Ghrelin, which causes hunger and is produced by the stomach
    • Leptin, which suppresses hunger and is produced by fat cells

    As fat cells accumulate, leptin levels also increase, but a person that has developed leptin resistance will not feel the appropriate amount of hunger suppression from the leptin, leading to chronic hunger unless large energy intake is sustained.














  • That kind of commit quality should only really be permissible on private projects, and as a reviewer, it’s arguably acceptable to reject PRs with this kind of history.

    You should be writing your commits to the benefit of the code reviewer - structure them in a logical fashion to tell the story about the changes you want to get merged.

    For non-trivial branches I usually soft reset to the point where all code is unstaged and uncommitted and then curate the commits to align with what the reviewer should be reading. It’s not uncommon for me to have several branches containing a single “wip”-commit which I amend onto while building up the full code for the branch.